Publications 2017

Managing Nut Allergy: A Remaining Clinical Challenge

Clinical study : Tree nuts allergies : Does a single nut allergy necessitate the dietary eviction of all tree nuts?
 

P. Eigenmann, A. Mazon, A. Nieto, D. Haddad, H. Brough, J.C. Caubet
 

 

Published in The Journal of Allergy and Clinical Immunology: In Practice. Volume 5, Issue 2, March–April 2017, Pages 296-300
 
 

Boosting Teenagers With Acellular Pertussis Vaccines Containing Recombinant or Chemically Inactivated Pertussis Toxin: A Randomized Clinical Trial

Clinical Study : PERTADO: A Phase II Randomized, Observer-blind Controlled Pilot Study to Compare the Safety and Immunogenicity of Acellular Pertussis Vaccines Including Chemically or Genetically-detoxified Pertussis Toxin in Adolescents Aged 11-15 Years Previously Immunized With Acellular Pertussis Vaccines
 

G. Blanchard Rohner, O. Chatzis, C.A. Siegrist, Klara M. Posfay-Barbe
 

Published in Clinical infectious diseases, Volume 68, Issue 7, 1 April 2019, Pages 1213–1222
 
 
 

TIRAP 180L Single Nucleotide Polymorphism is Associated with Susceptibility to Recurrent Pneumococcal Lower Respiratory Tract Infections in Children

This publication relates to a research project undertaken by the Paediatric Clinical Research Plateform : Infections respiratoires inférieures récurrentes chez le jeune enfant: une étude cas-témoins, prospective, s'intéressant aux déterminants immunologiques et génétiques, ainsi qu'aux conséquences cliniques

Johan N. Siebert, Lutz Hamann, Charlotte M. Verolet, Cécile Gameiro, Stephane Grillet, Claire-Anne Siegrist, Klara M. Posfay-Barbe
 

Published in Frontiers in Immunology, section Microbial Immunology, 07 August 2018

Time-To-Positivity of blood cultures in children with sepsis

Alexa Dierig, Christoph Berger, Philipp K. A. Agyeman, Sara Bernhard-Stirnemann,  Eric Giannoni,  Martin Stocker,  Klara M. Posfay-Barbe, Anita Niederer-Loher,  Christian R. Kahlert, Alex Donas, Paul Hasters, Christa Relly,  Thomas Riedel, Christoph Aebi,  Luregn J. Schlapbach, Ulrich Heininger and the Swiss Pediatric Sepsis Study
 

Blood cultures are essential for the diagnosis and further appropriate treatment in children with suspected sepsis. In most hospitals, children will be empirically treated or closely monitored for at least 48 h awaiting results of blood cultures. Several studies have challenged the optimal duration of empiric treatment in the era of continuously monitored blood culture systems. The aim of our study was to investigate time-to-positivity (TTP) of blood cultures in children with proven sepsis.
 

Published in Frontiers in Pediatrics, section Pediatrics Infectious Diseases, 08 August 2018

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